EGFR gene information
Gene symbol
EGFR
Full name
epidermal growth factor receptor
Gene type
protein-coding
Synonyms
ERBB; ERBB1; HER1; NISBD2; PIG61; mENA
Gene summary
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
More information
protein_atlas NCBI Ensembl

MutationInteractive chart

Gene expression profileInteractive chart

copy number alterations (CNA)Interactive chart